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Guanylyl Cyclase alpha 2 (GUCY1A2) Blocking Peptide | GUCY1A2 blocking peptide

Guanylyl Cyclase alpha 2 (GUCY1A2) Antibody (C-term) Blocking peptide

Gene Names
GUCY1A2; GC-SA2; GUC1A2
Synonyms
Guanylyl Cyclase alpha 2 (GUCY1A2); Guanylyl Cyclase alpha 2 (GUCY1A2) Antibody (C-term) Blocking peptide; Guanylate cyclase soluble subunit alpha-2; GCS-alpha-2; GUCY1A2; GUC1A2; GUCSA2; GUCY1A2 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human GUCY1A2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Sequence Length
732
Cellular Location
Cytoplasm.
Tissue Location
Isoform 1 is expressed in fetal brain, liver, colon, endothelium and testis. Isoform 2 is expressed only in liver, colon and endothelium
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for GUCY1A2 blocking peptide
Has guanylyl cyclase on binding to the beta-1 subunit.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
83,986 Da
NCBI Official Full Name
guanylate cyclase soluble subunit alpha-2 isoform 2
NCBI Official Synonym Full Names
guanylate cyclase 1 soluble subunit alpha 2
NCBI Official Symbol
GUCY1A2
NCBI Official Synonym Symbols
GC-SA2; GUC1A2
NCBI Protein Information
guanylate cyclase soluble subunit alpha-2
UniProt Protein Name
Guanylate cyclase soluble subunit alpha-2
Protein Family
UniProt Gene Name
GUCY1A2
UniProt Synonym Gene Names
GUC1A2; GUCSA2; GCS-alpha-2
UniProt Entry Name
GCYA2_HUMAN

NCBI Description

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

GUCY1A2: Has guanylyl cyclase on binding to the beta-1 subunit. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 4.6.1.2; Lyase; Guanylyl cyclase; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 11q21-q22

Cellular Component: guanylate cyclase complex, soluble; plasma membrane

Molecular Function: adenylate cyclase activity

Biological Process: signal transduction

Research Articles on GUCY1A2

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Product Notes

The GUCY1A2 gucy1a2 (Catalog #AAA9227616) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Guanylyl Cyclase alpha 2 (GUCY1A2), Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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