Glucose Transporter GLUT2 Blocking Peptide | GLUT2 blocking peptide
Glucose transporter GLUT2 Peptide
Immunocytochemistry: 1:100
Immunofluorescence: 1:100
Immunohistochemistry: 1:100
Western Blot: 1:500
Insulin-regulated facilitative glucose transporter.
NCBI and Uniprot Product Information
NCBI Description
transports glucose; may play a role in insulin response [RGD, Feb 2006]
Uniprot Description
GLUT4: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Its surface expression is regulated by insulin. Has two internalization sequences, a dileucine repeat present in the C-terminus and a FxxY motif in the amino-terminal end. Associates with an intracellular tubulo-vesicular compartment under low plasma conditions. The binding of insulin to the insulin receptor (a typosine kinase) leads to the rapid translocation of GLUT4 to the cell surface, increasing cellular glucose transport activity. Its translocation to the plasma membrane is also stimulated by exercise, but independent from insulin signaling. This insulin-independent pathway may be regulated by AMPK.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Cellular Component: cell surface; clathrin-coated vesicle; coated pit; cytoplasmic vesicle membrane; cytosol; endomembrane system; endosome; external side of plasma membrane; integral to membrane; integral to plasma membrane; intracellular membrane-bound organelle; lipid raft; membrane; multivesicular body; perinuclear region of cytoplasm; plasma membrane; sarcolemma; T-tubule; trans-Golgi network transport vesicle; vesicle; vesicle membrane
Molecular Function: D-glucose transmembrane transporter activity; glucose transmembrane transporter activity; protein binding
Biological Process: amylopectin biosynthetic process; brown fat cell differentiation; cellular response to insulin stimulus; glucose homeostasis; glucose transport; response to ethanol
Research Articles on GLUT2
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Product Notes
The GLUT2 slc2a4 (Catalog #AAA543765) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Glucose Transporter GLUT2 can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition. Confocal Microscopy||1:100 Immunocytochemistry: 1:100 Immunofluorescence: 1:100 Immunohistochemistry: 1:100 Western Blot: 1:500. Researchers should empirically determine the suitability of the GLUT2 slc2a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glucose Transporter GLUT2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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