GERP / TRIM8 Blocking Peptide | TRIM8 blocking peptide
GERP / TRIM8 Immunizing Peptide
For Blocking studies, reconstitute pellet in 200ul distilled water to obtain a 0.5mg/ml peptide solution.
It is currently untested in blocking applications.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]
Uniprot Description
TRIM8: Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1. Belongs to the TRIM/RBCC family.
Protein type: Ubiquitin conjugating system; EC 6.3.2.-; Ligase; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 10q24.3
Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleoplasm; PML body
Molecular Function: identical protein binding; ligase activity; protein homodimerization activity; zinc ion binding
Biological Process: activation of NF-kappaB transcription factor; innate immune response; negative regulation of viral transcription; negative regulation of virion penetration into host cell; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; protein ubiquitination; stem cell maintenance
Research Articles on TRIM8
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Product Notes
The TRIM8 trim8 (Catalog #AAA426744) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: C-YGQPSTKH YVTS. It is sometimes possible for the material contained within the vial of "GERP / TRIM8, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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