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FIBP blocking peptide

FIBP Antibody (Center) Blocking Peptide

Gene Names
FIBP; FGFIBP; FIBP-1
Synonyms
FIBP; FIBP Antibody (Center) Blocking Peptide; Acidic fibroblast growth factor intracellular-binding protein; aFGF intracellular-binding protein; FGF-1 intracellular-binding protein; FIBP blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of FIBP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
364
Cellular Location
Nucleus. Endomembrane system; Peripheral membrane protein. Note: Also associated with cytoplasmic membranes, particularly of mitochondria
Tissue Location
Highly expressed in heart, skeletal muscle and pancreas. Expressed at lower levels in brain. Also found in placenta, liver and kidney
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for FIBP blocking peptide
May be involved in mitogenic function of FGF1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
41,210 Da
NCBI Official Full Name
Acidic fibroblast growth factor intracellular-binding protein
NCBI Official Synonym Full Names
FGF1 intracellular binding protein
NCBI Official Symbol
FIBP
NCBI Official Synonym Symbols
FGFIBP; FIBP-1
NCBI Protein Information
acidic fibroblast growth factor intracellular-binding protein
UniProt Protein Name
Acidic fibroblast growth factor intracellular-binding protein
UniProt Gene Name
FIBP
UniProt Synonym Gene Names
aFGF intracellular-binding protein
UniProt Entry Name
FIBP_HUMAN

NCBI Description

Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

FIBP: May be involved in mitogenic function of FGF1. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: membrane; mitochondrion; nucleus

Molecular Function: fibroblast growth factor binding

Biological Process: fibroblast growth factor receptor signaling pathway

Research Articles on FIBP

Similar Products

Product Notes

The FIBP fibp (Catalog #AAA9219769) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "FIBP, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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