FCGR1A blocking peptide

FCGR1A Blocking Peptide

Gene Names

FCGR1A; CD64; FCRI; CD64A; IGFR1

Applications

Blocking/Control

Purity

The purity is >90%,tested by HPLC and MS.

Synonyms

FCGR1A; FCGR1A Blocking Peptide; CD64; CD64A; Fc fragment of IgG high affinity Ia receptor (CD64); Fc fragment of IgG; high affinity Ia; receptor for; Fc gamma receptor; Fc gamma receptor I A1; Fc gamma RI; Fc gamma RIA; Fc-gamma RI; Fc-gamma RIA; FCG1; FcgammaRIa; FCGR1; FCGR1_HUMAN; FcRI; FLJ18345; High affinity immunoglobulin gamma Fc receptor I; IGFR1; IgG Fc receptor I; Immunoglobulin G Fc receptor I; OTTHUMP00000013913; FCGR1A blocking peptide

Ordering
Cat. Num. AAA9625704 For Research Use Only!

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Applicable Applications for FCGR1A blocking peptide

Blocking/Control

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for FCGR1A blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

NCBI GI #

10835133

NCBI GeneID

2209

NCBI Accession #

NP_000557.1

NCBI GenBank Nucleotide #

NM_000566.3

UniProt Accession #

P12314; P12315; Q5QNW7; Q92495; Q92663

Molecular Weight

38,795 Da

NCBI Official Full Name

high affinity immunoglobulin gamma Fc receptor I

NCBI Official Synonym Full Names

Fc fragment of IgG, high affinity Ia, receptor (CD64)

NCBI Official Symbol

FCGR1A

NCBI Official Synonym Symbols

CD64; FCRI; CD64A; IGFR1

NCBI Protein Information

high affinity immunoglobulin gamma Fc receptor I; Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc gamma receptor; Fc-gamma RI; Fc-gamma receptor I A1; IgG Fc receptor I; fc-gamma RIA; fcgammaRIa

UniProt Protein Name

High affinity immunoglobulin gamma Fc receptor I

UniProt Gene Name

FCGR1A

UniProt Synonym Gene Names

FCG1; FCGR1; IGFR1; IgG Fc receptor I; FcRI; FcgammaRIa

UniProt Entry Name

FCGR1_HUMAN

NCBI Description

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]

Uniprot Description

FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q21.2-q21.3

Cellular Component: early endosome membrane; plasma membrane; integral to membrane

Molecular Function: protein binding; IgG binding; receptor signaling protein activity

Biological Process: antigen processing and presentation of peptide antigen via MHC class I; cytokine and chemokine mediated signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I; immune response; signal transduction; phagocytosis, engulfment

Research Articles on FCGR1A

1. An elevated neutrophil CD64 index is associated with both mucosal inflammation and an increased risk for clinical relapse in pediatric Crohn disease.

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Product Notes

The FCGR1A fcgr1a (Catalog #AAA9625704) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FCGR1A can be used in a range of immunoassay formats including, but not limited to, Blocking/Control. Researchers should empirically determine the suitability of the FCGR1A fcgr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCGR1A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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FCGR1A blocking peptide