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EXTL3 blocking peptide

EXTL3 Antibody (N-term) Blocking peptide

Gene Names
EXTL3; RPR; BOTV; REGR; EXTR1; EXTL1L
Synonyms
EXTL3; EXTL3 Antibody (N-term) Blocking peptide; Exostosin-like 3; EXT-related protein 1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Hereditary multiple exostoses gene isolog; Multiple exostosis-like protein 3; Putative tumor suppressor protein EXTL3; EXTL1L; EXTR1; KIAA0519; EXTL3 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
919
Cellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location
Ubiquitous. Expressed in keratinocytes.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for EXTL3 blocking peptide
Probable glycosyltransferase (By similarity). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
104,749 Da
NCBI Official Full Name
Exostosin-like 3
NCBI Official Synonym Full Names
exostosin like glycosyltransferase 3
NCBI Official Symbol
EXTL3
NCBI Official Synonym Symbols
RPR; BOTV; REGR; EXTR1; EXTL1L
NCBI Protein Information
exostosin-like 3
UniProt Protein Name
Exostosin-like 3
Protein Family
UniProt Gene Name
EXTL3
UniProt Synonym Gene Names
EXTL1L; EXTR1; KIAA0519
UniProt Entry Name
EXTL3_HUMAN

NCBI Description

This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012]

Uniprot Description

EXTL3: Probable glycosyltransferase. Belongs to the glycosyltransferase 47 family.

Protein type: Glycan Metabolism - heparan sulfate biosynthesis; EC 2.4.1.223; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane

Research Articles on EXTL3

Similar Products

Product Notes

The EXTL3 extl3 (Catalog #AAA9219362) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "EXTL3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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