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DPEP1 blocking peptide

DPEP1 Antibody(N-term) Blocking peptide

Gene Names
DPEP1; MDP; RDP; MBD1
Synonyms
DPEP1; DPEP1 Antibody(N-term) Blocking peptide; Dipeptidase 1; Dehydropeptidase-I; Microsomal dipeptidase; Renal dipeptidase; hRDP; MDP; RDP; DPEP1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
411
Cellular Location
Apical cell membrane; Lipid-anchor, GPI- anchor. Cell projection, microvillus membrane; Lipid-anchor, GPI- anchor. Note: Brush border membrane
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for DPEP1 blocking peptide
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
45,674 Da
NCBI Official Full Name
Dipeptidase 1
NCBI Official Synonym Full Names
dipeptidase 1 (renal)
NCBI Official Symbol
DPEP1
NCBI Official Synonym Symbols
MDP; RDP; MBD1
NCBI Protein Information
dipeptidase 1
UniProt Protein Name
Dipeptidase 1
Protein Family
UniProt Gene Name
DPEP1
UniProt Synonym Gene Names
MDP; RDP; hRDP
UniProt Entry Name
DPEP1_HUMAN

NCBI Description

The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

DPEP1: Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity. Belongs to the peptidase M19 family.

Protein type: EC 3.4.13.19; Membrane protein, GPI anchor; Protease

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: apical part of cell; extracellular space; plasma membrane

Molecular Function: caspase inhibitor activity; dipeptidase activity; metalloexopeptidase activity; protein binding; zinc ion binding

Biological Process: antibiotic metabolic process; glutathione metabolic process; homocysteine metabolic process; leukotriene metabolic process; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of cell migration; xenobiotic metabolic process

Research Articles on DPEP1

Similar Products

Product Notes

The DPEP1 dpep1 (Catalog #AAA9224446) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "DPEP1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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