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DNAJC13 blocking peptide

DNAJC13 Peptide

Gene Names
DNAJC13; RME8
Applications
Blocking (BL)
Synonyms
DNAJC13; DNAJC13 Peptide; DNAJ homolog subfamily C member 13; receptor-mediated endocytosis 8; RME8; DnaJ (Hsp40) homolog; subfamily C; member 13; DNAJC13 blocking peptide
Ordering
For Research Use Only!
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Length
2243
Applicable Applications for DNAJC13 blocking peptide
Blocking (BL)
Application Notes
DNAJC13 peptide is used for blocking the activity of DNAJC13 antibody.
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
18 amino acid peptide near the carboxy terminus of human DNAJC13.
Preparation and Storage
Store DNAJC13 peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
254,415 Da
NCBI Official Full Name
dnaJ homolog subfamily C member 13
NCBI Official Synonym Full Names
DnaJ (Hsp40) homolog, subfamily C, member 13
NCBI Official Symbol
DNAJC13
NCBI Official Synonym Symbols
RME8
NCBI Protein Information
dnaJ homolog subfamily C member 13; RME-8; DnaJ domain-containing protein RME-8; required for receptor-mediated endocytosis 8
UniProt Protein Name
DnaJ homolog subfamily C member 13
Protein Family
UniProt Gene Name
DNAJC13
UniProt Synonym Gene Names
KIAA0678; RME8; RME-8
UniProt Entry Name
DJC13_HUMAN

Uniprot Description

DNAJC13: Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR (PubMed:18256511, PubMed:18307993). Involved in the regulation of endosomal membrane tubulation and regulates th dynamics of SNX1 on the endosomal membrane; via association with FAM21 may link the WASH complex to the retromer SNX-BAR subcomplex (PubMed:24643499). {ECO:0000269|PubMed:18256511, ECO:0000269|PubMed:18307993, ECO:0000269|PubMed:24643499}. Interacts with FAM21C; mediates the association with the WASH complex (PubMed:24643499). {ECO:0000269|PubMed:24643499}

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: membrane; lysosomal membrane; early endosome membrane; endosome membrane

Molecular Function: protein binding

Biological Process: osteoblast differentiation; protein transport; endosome organization and biogenesis

Disease: Parkinson Disease 21

Research Articles on DNAJC13

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Product Notes

The DNAJC13 dnajc13 (Catalog #AAA153800) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DNAJC13 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). DNAJC13 peptide is used for blocking the activity of DNAJC13 antibody. Researchers should empirically determine the suitability of the DNAJC13 dnajc13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAJC13, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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