DDX28 blocking peptide

DDX28 Antibody (C-term) Blocking Peptide

• Gene Names: DDX28; MDDX28
• Synonyms: DDX28; DDX28 Antibody (C-term) Blocking Peptide; Probable ATP-dependent RNA helicase DDX28; Mitochondrial DEAD box protein 28; MDDX28; DDX28 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 540

• Cellular Location: Nucleus. Mitochondrion. Note: Transported between these two compartments. Nuclear localization depends on active RNA polymerase II transcription
• Tissue Location: Expressed in all tissues tested, including brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary and prostate
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for DDX28 blocking peptide

May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity.

NCBI and Uniprot Product Information

• NCBI GI #: 296434476
• NCBI GeneID: 55794
• UniProt Accession #: Q9NUL7
• Molecular Weight: 59,581 Da
• NCBI Official Full Name: Probable ATP-dependent RNA helicase DDX28
• NCBI Official Synonym Full Names: DEAD-box helicase 28
• NCBI Official Symbol: DDX28
• NCBI Official Synonym Symbols: MDDX28
• NCBI Protein Information: probable ATP-dependent RNA helicase DDX28
• UniProt Protein Name: Probable ATP-dependent RNA helicase DDX28
• Protein Family: Probable ATP-dependent RNA helicase
• UniProt Gene Name: DDX28
• UniProt Synonym Gene Names: MDDX28
• UniProt Entry Name: DDX28_HUMAN

NCBI Description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is intronless. It encodes an RNA-dependent ATPase. The encoded protein is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus. [provided by RefSeq, Jul 2008]

Uniprot Description

DDX28: May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity. Belongs to the DEAD box helicase family.

Protein type: EC 3.6.4.13; Hydrolase; RNA-binding

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoplasm; mitochondrion; nucleolus; nucleus

Molecular Function: ATP-dependent RNA helicase activity; rRNA binding

Biological Process: RNA secondary structure unwinding