DDA1 blocking peptide

DDA1 Blocking Peptide

Gene Names

SEC62; HTP1; TP-1; Dtrp1; TLOC1

Applications

Blocking/Control

Purity

The purity is >90%,tested by HPLC and MS.

Synonyms

DDA1; DDA1 Blocking Peptide; C19orf58; Cross immune reaction antigen PCIA1; DDA1_HUMAN; DET1 and DDB1 associated 1; DET1 and DDB1 associated protein 1; DET1- and DDB1-associated protein 1; MGC2594; PCIA-1; PCIA1; Placenta cross immune reaction antigen 1; Placenta cross-immune reaction antigen 1; DDA1 blocking peptide

Ordering
Cat. Num. AAA9621634 For Research Use Only!

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Applicable Applications for DDA1 blocking peptide

Blocking/Control

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for DDA1 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

NCBI GI #

4507525

NCBI GeneID

7095

NCBI Accession #

NP_003253

NCBI GenBank Nucleotide #

NP_003253.1

UniProt Accession #

Q9BW61; O00682; O00729; D3DNQ0; Q99442

Molecular Weight

45,862 Da

NCBI Official Full Name

translocation protein SEC62

NCBI Official Synonym Full Names

SEC62 homolog (S. cerevisiae)

NCBI Official Symbol

SEC62

NCBI Official Synonym Symbols

HTP1; TP-1; Dtrp1; TLOC1

NCBI Protein Information

translocation protein SEC62; hTP-1; translocation protein 1; membrane protein SEC62, S.cerevisiae, homolog of

UniProt Protein Name

DET1- and DDB1-associated protein 1

Protein Family

DET1- and DDB1-associated protein

UniProt Gene Name

DDA1

UniProt Synonym Gene Names

C19orf58; PCIA1; PCIA-1

UniProt Entry Name

DDA1_HUMAN

NCBI Description

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]

Uniprot Description

DDA1: May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD- E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins. Belongs to the DDA1 family.

Protein type: Ubiquitin conjugating system; Autophagy

Chromosomal Location of Human Ortholog: 19p13.11

Research Articles on DDA1

1. these studies identify TLOC1 and SKIL as driver genes at 3q26 and more broadly suggest that cooperating genes may be coamplified in other regions with somatic copy number gain.

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Product Notes

The DDA1 dda1 (Catalog #AAA9621634) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DDA1 can be used in a range of immunoassay formats including, but not limited to, Blocking/Control. Researchers should empirically determine the suitability of the DDA1 dda1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDA1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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DDA1 blocking peptide