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Cytokeratin 84 Blocking Peptide | KRT84 blocking peptide

Cytokeratin 84 Peptide

Gene Names
KRT84; HB4; KRTHB4
Applications
Blocking
Purity
Synthetic peptide Cytokeratin 84. (Note: the amino acid sequence is proprietary).
The purity is >98%.
Synonyms
Cytokeratin 84; Cytokeratin 84 Peptide; Cytokeratin-84; Keratin; type II cuticular Hb4; Keratin-84; Keratin84; Short name=K84; Type II hair keratin Hb4; Type-II keratin Kb24; KRT84; KRTHB4; KRT84 blocking peptide
Ordering
For Research Use Only!
Specificity
This peptide can be used with studies using MBS3006558 Cytokeratin 84 pAb.
Purity/Purification
Synthetic peptide Cytokeratin 84. (Note: the amino acid sequence is proprietary).
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
600
Applicable Applications for KRT84 blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for KRT84 blocking peptide
The Keratin multigene family is made of "soft" epithelial cytokeratins and "hard" hair Keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair Keratins are responsible for creating nails and hair. There are two types of Keratins: the acidic class I Keratin proteins and the basic/neutral class II Keratin proteins. Keratin 84, also known as KRT84, HB4 or KRTHB4, is a 600 amino acid protein that is expressed in hair follicles. Keratin 84 is a basic/neutral type II Keratin protein which heterodimerizes with type I Keratins to create hair and nails. The gene encoding Keratin 84 maps to human chromosome 12 which encodes over 1, 100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
keratin, type II cuticular Hb4
NCBI Official Synonym Full Names
keratin 84
NCBI Official Symbol
KRT84
NCBI Official Synonym Symbols
HB4; KRTHB4
NCBI Protein Information
keratin, type II cuticular Hb4
UniProt Protein Name
Keratin, type II cuticular Hb4
Protein Family
UniProt Gene Name
KRT84
UniProt Synonym Gene Names
KRTHB4; K84
UniProt Entry Name
KRT84_HUMAN

NCBI Description

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin is contained primarily in the filiform tongue papilla, among other hair keratins. [provided by RefSeq, Jul 2008]

Uniprot Description

K84: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: keratin filament

Molecular Function: structural constituent of cytoskeleton; structural constituent of epidermis

Biological Process: hair follicle development; regulation of keratinocyte differentiation

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Product Notes

The KRT84 krt84 (Catalog #AAA3006559) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Cytokeratin 84 can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the KRT84 krt84 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 84, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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