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CXXC1 blocking peptide

CXXC1 Antibody (Center) Blocking Peptide

Gene Names
CXXC1; CFP1; CGBP; SPP1; PCCX1; PHF18; hCGBP; ZCGPC1; HsT2645; 2410002I16Rik; 5830420C16Rik
Synonyms
CXXC1; CXXC1 Antibody (Center) Blocking Peptide; CXXC-type zinc finger protein 1; CpG-binding protein; PHD finger and CXXC domain-containing protein 1; CFP1; CGBP; PCCX1; PHF18; CXXC1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
656
Cellular Location
Nucleus speckle Note: Associated with euchromatin. During mitosis, excluded from condensed chromosomes
Tissue Location
Ubiquitous.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CXXC1 blocking peptide
Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
76,227 Da
NCBI Official Full Name
CXXC-type zinc finger protein 1
NCBI Official Synonym Full Names
CXXC finger protein 1
NCBI Official Symbol
CXXC1
NCBI Official Synonym Symbols
CFP1; CGBP; SPP1; PCCX1; PHF18; hCGBP; ZCGPC1; HsT2645; 2410002I16Rik; 5830420C16Rik
NCBI Protein Information
CXXC-type zinc finger protein 1
UniProt Protein Name
CXXC-type zinc finger protein 1
UniProt Gene Name
CXXC1
UniProt Synonym Gene Names
CFP1; CGBP; PCCX1; PHF18
UniProt Entry Name
CXXC1_HUMAN

NCBI Description

This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development. [provided by RefSeq, Sep 2015]

Uniprot Description

CXXC1: Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 18q12

Cellular Component: cytoplasm; histone methyltransferase complex; nuclear speck; nucleoplasm; nucleus

Molecular Function: histone lysine N-methyltransferase activity (H3-K4 specific); protein binding; unmethylated CpG binding

Biological Process: histone H3-K4 methylation; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent

Research Articles on CXXC1

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Product Notes

The CXXC1 cxxc1 (Catalog #AAA9221744) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CXXC1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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