COL21A1 blocking peptide

COL21A1 Antibody (N-term) Blocking peptide

• Gene Names: COL21A1; FP633; COLA1L
• Synonyms: COL21A1; COL21A1 Antibody (N-term) Blocking peptide; Collagen alpha-1(XXI) chain; COL1AL; COL21A1 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 957

• Cellular Location: Secreted, extracellular space, extracellular matrix. Cytoplasm. Note: Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle
• Tissue Location: Highly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta; moderately expressed in brain, colon, lung, prostate, spinal cord, salivary gland and vascular smooth-muscle cells and very weakly expressed in heart, liver, kidney, bone marrow, spleen, thymus, skeletal muscle, adrenal gland and peripheral leukocytes Expression in heart was higher in the right ventricle and atrium than in the left ventricle and atrium
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 74752071
• NCBI GeneID: 81578
• UniProt Accession #: Q96P44; Q49A51; Q71RF4; Q8WXV8; Q9H0V3; A6NIX5; B2R8J9
• Molecular Weight: 99,068 Da
• NCBI Official Full Name: Collagen alpha-1(XXI) chain
• NCBI Official Synonym Full Names: collagen type XXI alpha 1 chain
• NCBI Official Symbol: COL21A1
• NCBI Official Synonym Symbols: FP633; COLA1L
• NCBI Protein Information: collagen alpha-1(XXI) chain
• UniProt Protein Name: Collagen alpha-1(XXI) chain
• Protein Family: Collagen
• UniProt Gene Name: COL21A1
• UniProt Synonym Gene Names: COL1AL
• UniProt Entry Name: COLA1_HUMAN

NCBI Description

This gene encodes the alpha chain of type XXI collagen, a member of the FACIT (fibril-associated collagens with interrupted helices) collagen family. Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Uniprot Description

COL21A1: the alpha chain of type XXI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XXI collagen is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. An alternatively spliced transcript variant has been described, but its full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p12.3-p11.2|6p12.3-p11.2

Cellular Component: endoplasmic reticulum lumen; extracellular matrix; extracellular region