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CMAS blocking peptide

CMAS Blocking Peptide (C-term)

Gene Names
CMAS; CSS
Synonyms
CMAS; CMAS Blocking Peptide (C-term); N-acylneuraminate cytidylyltransferase; CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMAS blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 315-327 of Human CMAS
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
434
Cellular Location
Nucleus.
Tissue Location
Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CMAS blocking peptide
Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
29,561 Da
NCBI Official Full Name
N-acylneuraminate cytidylyltransferase
NCBI Official Synonym Full Names
cytidine monophosphate N-acetylneuraminic acid synthetase
NCBI Official Symbol
CMAS
NCBI Official Synonym Symbols
CSS
NCBI Protein Information
N-acylneuraminate cytidylyltransferase
UniProt Protein Name
N-acylneuraminate cytidylyltransferase
UniProt Gene Name
CMAS
UniProt Synonym Gene Names
CMP-NeuNAc synthase
UniProt Entry Name
NEUA_HUMAN

NCBI Description

This gene encodes an enzyme that converts N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc). This process is important in the formation of sialylated glycoprotein and glycolipids. This modification plays a role in cell-cell communications and immune responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Uniprot Description

CMAS: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). Belongs to the CMP-NeuNAc synthase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.7.7.43; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Transferase

Chromosomal Location of Human Ortholog: 12p12.1

Cellular Component: cytosol; membrane; nucleoplasm; nucleus

Molecular Function: N-acylneuraminate cytidylyltransferase activity

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Product Notes

The CMAS cmas (Catalog #AAA9229164) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CMAS, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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