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CHST10 blocking peptide

CHST10 Antibody (C-term) Blocking Peptide

Gene Names
CHST10; HNK1ST; HNK-1ST
Synonyms
CHST10; CHST10 Antibody (C-term) Blocking Peptide; Carbohydrate sulfotransferase 10; 282-; HNK-1 sulfotransferase; HNK-1ST; HNK1ST; HuHNK-1ST; CHST10 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
356
Cellular Location
Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location
In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues In brain, it is expressed at higher level in the frontal lobe
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CHST10 blocking peptide
Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
42,207 Da
NCBI Official Full Name
Carbohydrate sulfotransferase 10
NCBI Official Synonym Full Names
carbohydrate sulfotransferase 10
NCBI Official Symbol
CHST10
NCBI Official Synonym Symbols
HNK1ST; HNK-1ST
NCBI Protein Information
carbohydrate sulfotransferase 10
UniProt Protein Name
Carbohydrate sulfotransferase 10
UniProt Gene Name
CHST10
UniProt Synonym Gene Names
HNK-1ST; HNK1ST; HuHNK-1ST
UniProt Entry Name
CHSTA_HUMAN

NCBI Description

This protein encoded by this gene transfers sulfate to the C-3 hydroxyl of terminal glucuronic acid of protein- and lipid-linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer-1 (HNK-1) glycan; HNK-1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.[provided by RefSeq, Feb 2011]

Uniprot Description

HNK1ST: Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis. Belongs to the sulfotransferase 2 family.

Protein type: EC 2.8.2.-; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: Golgi apparatus; Golgi membrane; membrane

Molecular Function: HNK-1 sulfotransferase activity; sulfotransferase activity

Biological Process: cell adhesion

Research Articles on CHST10

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Product Notes

The CHST10 chst10 (Catalog #AAA9222628) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CHST10, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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