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CHCHD10 blocking peptide

CHCHD10 Antibody (N-term) Blocking Peptide

Gene Names
CHCHD10; IMMD; SMAJ; FTDALS2; N27C7-4; C22orf16
Synonyms
CHCHD10; CHCHD10 Antibody (N-term) Blocking Peptide; Coiled-coil-helix-coiled-coil-helix domain-containing protein 10; mitochondrial; Protein N27C7-4; C22orf16; CHCHD10 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
142
Cellular Location
Mitochondrion intermembrane space. Note: Enriched at the cristae junctions.
Tissue Location
Ubiquitously expressed. Higher expression is observed in heart and liver.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CHCHD10 blocking peptide
May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,149 Da
NCBI Official Full Name
coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial isoform b
NCBI Official Synonym Full Names
coiled-coil-helix-coiled-coil-helix domain containing 10
NCBI Official Symbol
CHCHD10
NCBI Official Synonym Symbols
IMMD; SMAJ; FTDALS2; N27C7-4; C22orf16
NCBI Protein Information
coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial
UniProt Protein Name
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial
UniProt Gene Name
CHCHD10
UniProt Synonym Gene Names
C22orf16
UniProt Entry Name
CHC10_HUMAN

NCBI Description

This gene encodes a mitochondrial protein that is enriched at cristae junctions in the intermembrane space. It may play a role in cristae morphology maintenance or oxidative phosphorylation. Mutations in this gene cause frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7 and 19. [provided by RefSeq, Aug 2014]

Uniprot Description

CHCHD10: May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure. {ECO:0000269|PubMed:24934289}

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 22q11.23

Cellular Component: mitochondrial intermembrane space; mitochondrion

Biological Process: ATP biosynthetic process; mitochondrion organization and biogenesis; oxidative phosphorylation

Disease: Frontotemporal Dementia And/or Amyotrophic Lateral Sclerosis 2; Myopathy, Isolated Mitochondrial, Autosomal Dominant; Spinal Muscular Atrophy, Jokela Type

Research Articles on CHCHD10

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Product Notes

The CHCHD10 chchd10 (Catalog #AAA9221599) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CHCHD10, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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