CD248 blocking peptide
CD248 Antibody (C-term) Blocking Peptide
Gene Names
CD248; TEM1; CD164L1
Synonyms
CD248; CD248 Antibody (C-term) Blocking Peptide; Endosialin; Tumor endothelial marker 1; CD164L1; TEM1; CD248 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human CD248. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
757
Cellular Location
Membrane; Single-pass type I membrane protein
Tissue Location
Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CD248 blocking peptide
May play a role in tumor angiogenesis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
46,241 Da
NCBI Official Full Name
Endosialin
NCBI Official Synonym Full Names
CD248 molecule
NCBI Official Symbol
CD248
NCBI Official Synonym Symbols
TEM1; CD164L1
NCBI Protein Information
endosialin
UniProt Protein Name
Endosialin
Protein Family
UniProt Gene Name
CD248
UniProt Synonym Gene Names
CD164L1; TEM1
UniProt Entry Name
CD248_HUMAN
Uniprot Description
CD248: May play a role in tumor angiogenesis. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: proteinaceous extracellular matrix
Research Articles on CD248
Similar Products
Product Notes
The CD248 cd248 (Catalog #AAA9226312) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CD248, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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