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Typical Testing Data/Standard Curve (for reference only)

Human plexin B1 ELISA Kit | PLXNB1 elisa kit

Human Plexin-B1, PLXNB1 ELISA Kit

Gene Names
PLXNB1; SEP; PLXN5; PLEXIN-B1
Reactivity
Human
Synonyms
plexin B1; Human Plexin-B1; PLXNB1 ELISA Kit; Human Plexin-B1 (PLXNB1) ELISA kit; KIAA0407; MGC149167; PLEXIN-B1; PLXN5; SEP; plexin 5; semaphorin receptor; PLXNB1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of human PLXNB1. No significant cross-reactivity or interference between human PLXNB1 and analogues was observed.
Sequence Length
2135
Samples
Serum, plasma, tissue homogenates, cell lysates
Assay Type
Quantitative Sandwich
Detection Range
78 pg/ml-5000 pg/ml
Sensitivity
< 19.5 pg/ml
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for PLXNB1 elisa kit
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PLXNB1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PLXNB1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PLXNB1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PLXNB1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
232,298 Da
NCBI Official Full Name
plexin-B1
NCBI Official Synonym Full Names
plexin B1
NCBI Official Symbol
PLXNB1
NCBI Official Synonym Symbols
SEP; PLXN5; PLEXIN-B1
NCBI Protein Information
plexin-B1; plexin 5; semaphorin receptor SEP
UniProt Protein Name
Plexin-B1
Protein Family
UniProt Gene Name
PLXNB1
UniProt Synonym Gene Names
KIAA0407; PLXN5; SEP
UniProt Entry Name
PLXB1_HUMAN

Uniprot Description

PLXNB1: Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the plexin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: integral to plasma membrane; extracellular region; plasma membrane; intracellular

Molecular Function: protein binding; transmembrane receptor activity; semaphorin receptor activity; GTPase activating protein binding; receptor activity; semaphorin receptor binding

Biological Process: positive regulation of phosphoinositide 3-kinase cascade; regulation of cell shape; axon guidance; cell migration; negative regulation of osteoblast proliferation; positive regulation of axonogenesis; negative regulation of cell adhesion; signal transduction; neurite morphogenesis; regulation of cytoskeleton organization and biogenesis

Research Articles on PLXNB1

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Product Notes

The Human PLXNB1 plxnb1 (Catalog #AAA946846) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA946846 ELISA Kit recognizes Human PLXNB1. It is sometimes possible for the material contained within the vial of "plexin B1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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