B3GALT6 blocking peptide
B3GALT6 Antibody (C-term) Blocking Peptide
NCBI and Uniprot Product Information
NCBI Description
The enzyme encoded by this intronless gene is a beta-1,3-galactosyltransferase found in the medial Golgi apparatus, where it catalyzes the transfer of galactose from UDP-galactose to substrates containing a terminal beta-linked galactose moiety. The encoded enzyme has a particular affinity for galactose-beta-1,4-xylose found in the linker region of glycosamines. This enzyme is required for glycosaminoglycan synthesis. [provided by RefSeq, Jun 2013]
Uniprot Description
B3GALT6: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substrates with terminal glucosamine or galactosamine residues. Belongs to the glycosyltransferase 31 family.
Protein type: Glycan Metabolism - chondroitin sulfate biosynthesis; Transferase; Membrane protein, integral; Glycan Metabolism - heparan sulfate biosynthesis; EC 2.4.1.134
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: Golgi medial cisterna; Golgi membrane; membrane
Molecular Function: galactosylxylosylprotein 3-beta-galactosyltransferase activity; UDP-galactosyltransferase activity
Biological Process: glycosaminoglycan biosynthetic process; glycosaminoglycan metabolic process
Disease: Ehlers-danlos Syndrome, Progeroid Type, 2; Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 1, With Or Without Fractures
Research Articles on B3GALT6
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Product Notes
The B3GALT6 b3galt6 (Catalog #AAA9225471) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "B3GALT6, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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