ATP5J2 blocking peptide

ATP5J2 Antibody (Center) Blocking peptide

• Gene Names: ATP5J2; ATP5JL
• Synonyms: ATP5J2; ATP5J2 Antibody (Center) Blocking peptide; ATP synthase subunit f; mitochondrial; ATP5JL; ATP5J2 blocking peptide

• Form/Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
• Sequence Length: 94

• Cellular Location: Mitochondrion. Mitochondrion inner membrane; Single-pass membrane protein
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ATP5J2 blocking peptide

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

NCBI and Uniprot Product Information

• NCBI GI #: 4757812
• NCBI GeneID: 9551
• NCBI Accession #: NP_004880.1
• NCBI GenBank Nucleotide #: NM_004889.3
• UniProt Accession #: P56134; O76079; Q6IBB3; Q96L83; Q9BTI8; C9J8H9; F8W7V3
• Molecular Weight: 5,741 Da
• NCBI Official Full Name: ATP synthase subunit f, mitochondrial isoform 2a
• NCBI Official Synonym Full Names: ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2
• NCBI Official Symbol: ATP5J2
• NCBI Official Synonym Symbols: ATP5JL
• NCBI Protein Information: ATP synthase subunit f, mitochondrial
• UniProt Protein Name: ATP synthase subunit f, mitochondrial
• UniProt Gene Name: ATP5J2
• UniProt Synonym Gene Names: ATP5JL
• UniProt Entry Name: ATPK_HUMAN

NCBI Description

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the f subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. This gene has multiple pseudogenes. Naturally occurring read-through transcription also exists between this gene and the downstream pentatricopeptide repeat domain 1 (PTCD1) gene. [provided by RefSeq, Nov 2010]

Uniprot Description

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.