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ARL6IP1 blocking peptide

ARL6IP1 Antibody (N-term) Blocking Peptide

Gene Names
ARL6IP1; AIP1; ARMER; SPG61; ARL6IP
Synonyms
ARL6IP1; ARL6IP1 Antibody (N-term) Blocking Peptide; ADP-ribosylation factor-like protein 6-interacting protein 1; ARL-6-interacting protein 1; Aip-1; ARL6IP; KIAA0069; ARL6IP1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
203
Cellular Location
Endomembrane system; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note: Predominantly localized to intracytoplasmic membranes
Tissue Location
Expressed in all hematopoietic cell lineages, but the highest level of expression is found in early myeloid progenitor cells. Expressed in brain, bone marrow, thymus and lung. Expressed at low level in liver, kidney and spleen. Not detected in heart.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ARL6IP1 blocking peptide
May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
17,158 Da
NCBI Official Full Name
ADP-ribosylation factor-like protein 6-interacting protein 1
NCBI Official Synonym Full Names
ADP ribosylation factor like GTPase 6 interacting protein 1
NCBI Official Symbol
ARL6IP1
NCBI Official Synonym Symbols
AIP1; ARMER; SPG61; ARL6IP
NCBI Protein Information
ADP-ribosylation factor-like protein 6-interacting protein 1
UniProt Protein Name
ADP-ribosylation factor-like protein 6-interacting protein 1
UniProt Gene Name
ARL6IP1
UniProt Synonym Gene Names
; ARL-6-interacting protein 1; Aip-1
UniProt Entry Name
AR6P1_HUMAN

NCBI Description

This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Uniprot Description

ARL6IP: May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Belongs to the ARL6ip family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p12-p11.2

Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to membrane; membrane; translocon complex

Molecular Function: protein binding

Biological Process: cotranslational protein targeting to membrane; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of L-glutamate transport

Disease: Spastic Paraplegia 61, Autosomal Recessive

Research Articles on ARL6IP1

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Product Notes

The ARL6IP1 arl6ip1 (Catalog #AAA9221871) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ARL6IP1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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