Rabbit anti-Human ARL6IP1 Polyclonal Antibody | anti-ARL6IP1 antibody

ARL6IP1, NT (ARL6IP1, ARL6IP, KIAA0069, ADP-ribosylation factor-like protein 6-interacting protein 1) (FITC)

Cat. Num. AAA6275163

• Gene Names: ARL6IP1; AIP1; ARMER; SPG61; ARL6IP
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ARL6IP1; Polyclonal Antibody; NT (ARL6IP1; ARL6IP; KIAA0069; ADP-ribosylation factor-like protein 6-interacting protein 1) (FITC); ADP-ribosylation factor-like protein 6-interacting protein 1; anti-ARL6IP1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-ARL6IP1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ARL6IP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ARL6IP1.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ARL6IP1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ARL6IP1 antibody detected the ARL6IP1 protein (arrow).)

Related Product Information for anti-ARL6IP1 antibody

ARL6IP1 may be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.

Product Categories/Family for anti-ARL6IP1 antibody

Antibodies; GTPase; Rab; Ras; Rho Proteins

References

Guo, F., et al. Oncol. Rep. 23(5):1449-1455(2010). Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009). Lamesch, P., et al. Genomics 89(3):307-315(2007). Lui, H.M., et al. Mol. Cancer Res. 1(7):508-518(2003). Pettersson, M., et al. Genomics 68(3):351-354(2000).

NCBI and Uniprot Product Information

• NCBI GI #: 24308007
• NCBI GeneID: 23204
• NCBI Accession #: NP_055976.1
• NCBI GenBank Nucleotide #: NM_015161.1
• UniProt Accession #: Q15041; B7Z6S5; B7Z791; F5GXP4
• Molecular Weight: 17,158 Da
• NCBI Official Full Name: ADP-ribosylation factor-like protein 6-interacting protein 1
• NCBI Official Synonym Full Names: ADP-ribosylation factor-like 6 interacting protein 1
• NCBI Official Symbol: ARL6IP1
• NCBI Official Synonym Symbols: AIP1; ARMER; SPG61; ARL6IP
• NCBI Protein Information: ADP-ribosylation factor-like protein 6-interacting protein 1; ARL-6-interacting protein 1; aip-1; apoptotic regulator in the membrane of the endoplasmic reticulum
• UniProt Protein Name: ADP-ribosylation factor-like protein 6-interacting protein 1
• Protein Family: ADP-ribosylation factor-like protein 6-interacting protein
• UniProt Gene Name: ARL6IP1
• UniProt Synonym Gene Names: ARL6IP; KIAA0069; ARL-6-interacting protein 1; Aip-1
• UniProt Entry Name: AR6P1_HUMAN

NCBI Description

This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Uniprot Description

ARL6IP: May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Belongs to the ARL6ip family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p12-p11.2

Cellular Component: membrane; integral to membrane; translocon complex; cytosol

Molecular Function: protein binding

Biological Process: cotranslational protein targeting to membrane

Disease: Spastic Paraplegia 61, Autosomal Recessive