APPBP2 blocking peptide

APPBP2 Antibody (Center) Blocking Peptide

• Gene Names: APPBP2; PAT1; APP-BP2; HS.84084
• Synonyms: APPBP2; APPBP2 Antibody (Center) Blocking Peptide; Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1; KIAA0228; PAT1; APPBP2 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 585

• Cellular Location: Nucleus. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note: Associated with membranes and microtubules
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for APPBP2 blocking peptide

May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

NCBI and Uniprot Product Information

• NCBI GI #: 50400598
• NCBI GeneID: 10513
• UniProt Accession #: Q92624; O95095; Q8WVC9; A8K862
• Molecular Weight: 66,853 Da
• NCBI Official Full Name: Amyloid protein-binding protein 2
• NCBI Official Synonym Full Names: amyloid beta precursor protein binding protein 2
• NCBI Official Symbol: APPBP2
• NCBI Official Synonym Symbols: PAT1; APP-BP2; HS.84084
• NCBI Protein Information: amyloid protein-binding protein 2
• UniProt Protein Name: Amyloid protein-binding protein 2
• Protein Family: Amyloid protein-binding protein
• UniProt Gene Name: APPBP2
• UniProt Synonym Gene Names: KIAA0228; PAT1; APP-BP2
• UniProt Entry Name: APBP2_HUMAN

NCBI Description

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

APPBP2: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

Protein type: Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 17q23.2

Cellular Component: cytoplasm; cytoplasmic vesicle membrane; microtubule associated complex

Molecular Function: microtubule motor activity; protein binding

Biological Process: intracellular protein transport; intracellular transport