ApoL2 blocking peptide

ApoL2 (R229) Peptide

Cat. Num. AAA3003382

• Applications: Blocking
• Purity: Synthetic peptide ApoL2 (R229). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Synonyms: ApoL2; ApoL2 (R229) Peptide; Apolipoprotein L2; Apolipoprotein L-2; ApoL-2; APOL2; ApoL2 blocking peptide

• Specificity: This peptide can be used with studies using MBS3003381 ApoL2 (R229) pAb.
• Purity/Purification: Synthetic peptide ApoL2 (R229). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Form/Format: 1 mg/ml in DI water.
• Sequence Length: 337

• Applicable Applications for ApoL2 blocking peptide: Blocking
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Related Product Information for ApoL2 blocking peptide

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL 1-6, which are associated with large high density type lipoproteins (HDL). The human apoL family maps to chromosome 22q12.3 within a 127, 000-bp region. ApoL2 and apoL3 may allow the binding of lipids to organ-elles or may be involved in the movement of lipids in the cytoplasm. ApoL2 localizes to the cytoplasm and is widely expressed, with the highest levels observed in the lung, thymus, pancreas, placenta, adult brain and prostate. The apoL2 protein is also detected in the spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis and fetal brain and liver. ApoL3 also localizes to the cytoplasm and is widely expressed, with highest levels detected in the prostate, lung and placenta. It is also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland. Lower levels of apoL3 are observed in the brain, heart, fetal liver, pancreas and testis.

NCBI and Uniprot Product Information

• NCBI GI #: 13562090
• NCBI Accession #: NP_112092.1
• NCBI GenBank Nucleotide #: NP_112092.1
• UniProt Accession #: Q9BQE5
• NCBI Official Full Name: apolipoprotein L2
• UniProt Protein Name: Apolipoprotein L2
• Protein Family: Apolipoprotein
• UniProt Gene Name: APOL2
• UniProt Synonym Gene Names: ApoL-II
• UniProt Entry Name: APOL2_HUMAN

Uniprot Description

APOL2: May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles. Belongs to the apolipoprotein L family.

Chromosomal Location of Human Ortholog: 22q12

Cellular Component: endoplasmic reticulum membrane; membrane; extracellular region

Molecular Function: lipid binding; high-density lipoprotein binding; receptor binding

Biological Process: cholesterol metabolic process; maternal process involved in pregnancy; multicellular organismal development; acute-phase response; lipoprotein metabolic process; lipid metabolic process; lipid transport

Disease: Schizophrenia