AP3S1 blocking peptide

AP3S1 Peptide

Cat. Num. AAA152117

• Gene Names: AP3S1; CLAPS3; Sigma3A
• Applications: Blocking (BL)
• Synonyms: AP3S1; AP3S1 Peptide; CLAPS3; Sigma3A; AP-3 complex subunit sigma-1; AP-3 complex subunit sigma-3A; Sigma3A-adaptin; adaptor-related protein complex 3; sigma 1 subunit; AP3S1 blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 193

• Applicable Applications for AP3S1 blocking peptide: Blocking (BL)
• Application Notes: AP3S1 peptide is used for blocking the activity of AP3S1 antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 19 amino acids near the center of human AP3S1.
• Preparation and Storage: Store AP3S1 peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

• NCBI GI #: 4502861
• NCBI GeneID: 1176
• NCBI Accession #: NP_001275
• NCBI GenBank Nucleotide #: NM_001284.2
• UniProt Accession #: Q92572; O00647; O00676; O00721; O00727; Q53XL4; Q6ICQ2
• Molecular Weight: 21,732 Da
• NCBI Official Full Name: AP-3 complex subunit sigma-1
• NCBI Official Synonym Full Names: adaptor-related protein complex 3, sigma 1 subunit
• NCBI Official Symbol: AP3S1
• NCBI Official Synonym Symbols: CLAPS3; Sigma3A
• NCBI Protein Information: AP-3 complex subunit sigma-1; sigma3A-adaptin; sigma-3A-adaptin; sigma-adaptin 3a; AP-3 complex sigma-3A subunit; AP-3 complex subunit sigma-3A; adapter-related protein complex 3 sigma-1 subunit; adapter-related protein complex 3 subunit sigma-1; adaptor-related protein complex 3 subunit sigma-1; clathrin-associated/assembly/adapter protein, small 3; clathrin-associated/assembly/adaptor protein, small 3 (22kD)
• UniProt Protein Name: AP-3 complex subunit sigma-1
• Protein Family: AP-3 complex
• UniProt Gene Name: AP3S1
• UniProt Synonym Gene Names: CLAPS3; Sigma3A-adaptin
• UniProt Entry Name: AP3S1_HUMAN

Uniprot Description

AP3S1: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Belongs to the adaptor complexes small subunit family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5q22

Cellular Component: Golgi apparatus; transport vesicle; cytoplasmic vesicle membrane; AP-type membrane coat adaptor complex

Molecular Function: protein binding; transporter activity; protein transporter activity

Biological Process: intracellular protein transport; anterograde synaptic vesicle transport; insulin receptor signaling pathway; anterograde axon cargo transport