ACAD11 blocking peptide

ACAD11 Blocking Peptide

Cat. Num. AAA9628168

• Gene Names: ACAD11; ACAD-11
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: ACAD11; ACAD11 Blocking Peptide; 5730439E10Rik; 62113 protein; ACAD 11; ACAD-11; Acad11; ACD11_HUMAN; Acyl CoA dehydrogenase family member 11; Acyl Coenzyme A dehydrogenase family member 11; Acyl-CoA dehydrogenase family member 11; AI987948; FLJ12592; MGC150619; Putative acyl CoA dehydrogenase; RGD1306270; ACAD11 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for ACAD11 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ACAD11 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 38505218
• NCBI GeneID: 84129
• NCBI Accession #: NP_115545.3
• NCBI GenBank Nucleotide #: NM_032169.4
• UniProt Accession #: Q709F0; Q08AF0; Q658N9; Q658Y2; Q6ZND2; Q8WUT6; Q9H9R3
• Molecular Weight: 87283
• NCBI Official Full Name: acyl-CoA dehydrogenase family member 11
• NCBI Official Synonym Full Names: acyl-CoA dehydrogenase family, member 11
• NCBI Official Symbol: ACAD11
• NCBI Official Synonym Symbols: ACAD-11
• NCBI Protein Information: acyl-CoA dehydrogenase family member 11; 62113 protein; acyl-Coenzyme A dehydrogenase family, member 11
• UniProt Protein Name: Acyl-CoA dehydrogenase family member 11
• UniProt Gene Name: ACAD11
• UniProt Synonym Gene Names: ACAD-11
• UniProt Entry Name: ACD11_HUMAN

NCBI Description

This gene encodes an acyl-CoA dehydrogenase enzyme with a preference for carbon chain lengths between 20 and 26. Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis 3 (adolescent)) and this gene. [provided by RefSeq, Aug 2015]

Uniprot Description

Function: Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA. Ref.6

Catalytic activity: Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.

Cofactor: FAD. Ref.7

Subunit structure: Homodimer. Ref.7

Subcellular location: Peroxisome

By similarity. Mitochondrion. Note: Has been detected associated with mitochondrial membrane, but no matrix, in kidney and cerebellum, as well as in a neuroblastoma cell line, but not in skin fibroblasts, where it is observed in cytoplasmic vesicles (Ref.6). No mitochondrial targeting signals could be predicted for any known isoform, including a putative isoform starting at Met-316. Ref.6

Tissue specificity: Widely expressed with highest levels in brain followed by liver, heart and kidney. Ref.6

Sequence similarities: Belongs to the acyl-CoA dehydrogenase family.

Sequence caution: The sequence BAB14158.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.