Rat Baculoviral IAP repeat-containing protein 5 ELISA Kit | Birc5 elisa kit
Rat Baculoviral IAP repeat-containing protein 5 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
functions as an inhibitor of programmed cell death [RGD, Feb 2006]
Uniprot Description
Survivin: an apoptosis inhibitor that is expressed during the G2/M phase of the cell cycle. Associates with the microtubules of the mitotic spindle and any disruption results in the loss of apoptosis activity. May play a role in neoplasia. Inhibitor of caspase-3 and caspase-7. Two splice variant isoforms have been described.
Protein type: Apoptosis
Cellular Component: apical plasma membrane; centriole; chromosome, pericentric region; cytoplasm; cytoplasmic microtubule; cytosol; interphase microtubule organizing center; midbody; nuclear chromosome; nucleus; spindle microtubule
Molecular Function: caspase inhibitor activity; chaperone binding; cofactor binding; cysteine protease inhibitor activity; enzyme binding; identical protein binding; microtubule binding; protein heterodimerization activity; protein homodimerization activity; Ran GTPase binding; tubulin binding; ubiquitin-protein ligase activity; zinc ion binding
Biological Process: cell division; chromosome segregation; establishment of chromosome localization; G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization and biogenesis; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of neuron apoptosis; negative regulation of transcription, DNA-dependent; positive regulation of cell cycle; positive regulation of exit from mitosis; positive regulation of mitotic cell cycle; protein amino acid phosphorylation; protein complex localization; protein ubiquitination; regulation of mitotic cell cycle; regulation of signal transduction; response to drug; response to glucocorticoid stimulus; response to peptide hormone stimulus; transcription, DNA-dependent
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Product Notes
The Rat Birc5 birc5 (Catalog #AAA2885255) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885255 ELISA Kit recognizes Rat Birc5. It is sometimes possible for the material contained within the vial of "Baculoviral IAP repeat-containing protein 5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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