Cat Baculoviral IAP repeat-containing protein 5 ELISA Kit | BIRC5 elisa kit

Cat Baculoviral IAP repeat-containing protein 5 (BIRC5) ELISA Kit

Cat. Num. AAA284655

• Reactivity: Cat
• Synonyms: Baculoviral IAP repeat-containing protein 5; Cat Baculoviral IAP repeat-containing protein 5 (BIRC5) ELISA Kit; BIRC5 elisa kit

• Reactivity: Cat
• Specificity: This assay has high sensitivity and excellent specificity for detection of Cat BIRC5. No significant cross-reactivity or interference between Cat BIRC5 and analogues was observed.
• Sequence Length: 165

• Samples: Serum, Plasma, Other biological fluids
• Assay Type: Sandwich
• Sample Volume: 1-200 uL
• Precision: Intra-assay Precision (Precision within an assay); Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.; Inter-assay Precision (Precision between assays); Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.; CV (%) = SD/meanX100; Intra-Assay: CV; Inter-Assay: CV
• Detection Wavelength: 450 nm
• Preparation and Storage: Store at 2-8 degree C.

Related Product Information for BIRC5 elisa kit

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate BIRC5 in samples. An antibody specific for BIRC5 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyBIRC5 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for BIRC5 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of BIRC5 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 57163813
• NCBI GeneID: 493835
• NCBI Accession #: NP_001009280.1
• NCBI GenBank Nucleotide #: NM_001009280.1
• UniProt Accession #: Q6I6F4
• Molecular Weight: 16,393 Da
• NCBI Official Full Name: baculoviral IAP repeat-containing protein 5
• NCBI Official Symbol: BIRC5
• NCBI Protein Information: baculoviral IAP repeat-containing protein 5
• UniProt Protein Name: Baculoviral IAP repeat-containing protein 5
• Protein Family: Baculoviral IAP repeat-containing protein
• UniProt Gene Name: BIRC5

Uniprot Description

Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. Involved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7.