Structure
WAY 163909 Biochemical
WAY 163909
Purity
>98% (HPLC)
Synonyms
WAY 163909; WAY163909; WAY-163909; WAY 163909 biochemical
Purity/Purification
>98% (HPLC)
Target
5-HT Receptor
Receptor
5-HT Receptor
Chemical Name
(11R, 15R)-7, 10-diazatetracyclo[8.5.1.0^{5, 16}.0^{11, 15}]hexadeca-1, 3, 5(16)-triene
SMILES
[H][C@]1(CCC[C@]21[H])N3CCNCC4=C3C2=CC=C4
Molecular Formula
C14H18N2
CAS Number
428868-32-0
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for WAY 163909 biochemical
A highly potent, subtype-selective agonist of 5-HT2C receptor with Ki of 10.5nM, >20-fold selectivity over 5-HT2A and 5-HT2B receptor subtypes (IC50=212 and 485nM, respectively); stimulates the mobilization of intracellular calcium in CHO cells stably expressing the human 5-HT2C with EC50 of 8nM; produces a dose-dependent reduction in food intake in rat (ED50=2.93mg/kg), also exhibits preclinical antipsychotic-like activity in vivo.
Product Categories/Family for WAY 163909 biochemical
References
1. Dunlop J, et al. J Pharmacol Exp Ther. 2005 May; 313 (2):862-9.
2. Marquis KL, et al. J Pharmacol Exp Ther. 2007 Jan; 320 (1):486-96.
3. Rosenzweig-Lipson S, et al. Psychopharmacology (Berl). 2007 Jun; 192 (2):159-70.
4. Grauer SM, et al. Psychopharmacology (Berl). 2009 May; 204 (1):37-48.
2. Marquis KL, et al. J Pharmacol Exp Ther. 2007 Jan; 320 (1):486-96.
3. Rosenzweig-Lipson S, et al. Psychopharmacology (Berl). 2007 Jun; 192 (2):159-70.
4. Grauer SM, et al. Psychopharmacology (Berl). 2009 May; 204 (1):37-48.
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Product Notes
The WAY 163909 (Catalog #AAA3604453) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "WAY 163909, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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