Structure
S-Adenosyl-L-methionine disulfate tosylate Biochemical
S-Adenosyl-L-methionine disulfate tosylate
Purity
>=95% by HPLC
Synonyms
S-Adenosyl-L-methionine disulfate tosylate; AdoMet SAM disulfate p-toluenesulfonate; SAMe; S-Adenosyl-L-methionine disulfate tosylate biochemical
Purity/Purification
>=95% by HPLC
Form/Format
Appearance: White to off-white solid
CAS Number
97540-22-2
Structure Available?
Yes
Cell-Permeable?
No
MDL Number
MFCD01674068
PubChem CID
163657
Solubility/Reconstitution Instructions
H?O (~100 mg/ml)
SMILES
CC1=CC=C(C=C1)S(=O)(=O)[O-].C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O.OS(=O)(=O)[O-].[O-]S(=O)(=O)[O-]
InChi
InChI=1S/C15H22N6O5S.C7H8O3S.2H2O4S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;1-6-2-4-7(5-3-6)11(8,9)10;2*1-5(2,3)4/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);2-5H,1H3,(H,8,9,10);2*(H2,1,2,3,4)/p-3/t7-,8+,10+,11+,14+,27?;;;/m0.../s1
InChi Key
XDCFCHNAIMYBAZ-XQVUROGGSA-K
Handling
Protect from moisture
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Shelf Life: 24 months
Structure
Structure
Related Product Information for S-Adenosyl-L-methionine disulfate tosylate biochemical
Background: A methyl donor and a cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. SAM is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells.
Product Categories/Family for S-Adenosyl-L-methionine disulfate tosylate biochemical
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Product Notes
The S-Adenosyl-L-methionine disulfate tosylate (Catalog #AAA842054) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "S-Adenosyl-L-methionine disulfate tosylate, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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