Structure
RP-5063 Biochemical
RP-5063
Purity
>98% (HPLC)
Synonyms
RP-5063; RP5063; RP-5063 biochemical
Purity/Purification
>98% (HPLC)
Target
Dopamine Receptor
Receptor
Dopamine Receptor
Chemical Name
6-(4-(4-(2, 3-dichlorophenyl)piperazin-1-yl)butoxy)-2H-benzo[b][1, 4]oxazin-3(4H)-one
SMILES
C1CN(CCN1CCCCOC2=CC3=C(C=C2)OCC(=O)N3)C4=C(C(=CC=C4)Cl)Cl
Molecular Formula
C22H25Cl2N3O3
CAS Number
1239729-06-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for RP-5063 biochemical
RP-5063 (Brilaroxazine) is a multimodal dopamine and serotonin modulator with partial agonist activity at DA D2, D3, D4, 5-HT1A, and 5-HT2ARs, and antagonist activity at 5-HT2B, 5-HT6 and 5-HT7Rs; produces dose-dependent reductions in pulmonary blood vessel wall thickness and proportion of muscular vessels, blocks MCT-induced increases in the plasma cytokines TNFalpha, IL-1beta, and IL-6 in vivo; prevents Sugen 5416-hypoxia-induced pulmonary arterial hypertension in rats; improves declarative memory and psychosis in mouse models of schizophrenia. Schizophrenia Phase 2 Clinical
Product Categories/Family for RP-5063 biochemical
References
1. Bhat L, et al. Eur J Pharmacol. 2017 Sep 5; 810:83-91.
2. Rajagopal L, et al. Behav Brain Res. 2017 Aug 14; 332:180-199.
3. Bhat L, et al. Eur J Pharmacol. 2017 Sep 5; 810:92-99.
2. Rajagopal L, et al. Behav Brain Res. 2017 Aug 14; 332:180-199.
3. Bhat L, et al. Eur J Pharmacol. 2017 Sep 5; 810:92-99.
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Product Notes
The RP-5063 (Catalog #AAA3600967) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RP-5063, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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