Structure
Rosiglitazone Biochemical
Rosiglitazone
Purity
>98% (HPLC)
Synonyms
Rosiglitazone; BRL-49653; Rosiglitazone biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=180mg/mL
Target
PPAR
Receptor
PPAR
Chemical Name
2, 4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]
SMILES
O=C(N1)SC(CC2=CC=C(OCCN(C)C3=NC=CC=C3)C=C2)C1=O
Molecular Formula
C18H19N3O3S
CAS Number
122320-73-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Rosiglitazone biochemical
A potent and selective PPARgamma agonist that binds to the PPARgamma ligand-binding domain with a Kd of 40nM; an antidiabetic agent that has been used as an oral hypoglycemic agent in the treatment of Type II diabetes; also inhibits TRP channels TRPM2 and TRPM3 with IC50 of 22.5uM and 5-10uM, respectively; also increases klotho and decreases Wnt5A in tumor cells. Diabetes Approved
Product Categories/Family for Rosiglitazone biochemical
References
1. Lehmann JM, et al. J Biol Chem. 1995 Jun 2; 270 (22):12953-6.
2. Majeed Y, et al. Mol Pharmacol. 2011 Jun; 79 (6):1023-30.
3. Behera R, et al. Clin Cancer Res. 2017 Jun 15; 23 (12):3181-3190.
2. Majeed Y, et al. Mol Pharmacol. 2011 Jun; 79 (6):1023-30.
3. Behera R, et al. Clin Cancer Res. 2017 Jun 15; 23 (12):3181-3190.
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Product Notes
The Rosiglitazone (Catalog #AAA3600852) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Rosiglitazone, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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