Structure
PF-06885249 Biochemical
PF-06885249
Purity
>98% (HPLC)
Synonyms
PF-06885249; PF06885249; PF-06885249 biochemical
Purity/Purification
>98% (HPLC)
Target
AMPK
Receptor
AMPK
Chemical Name
6-chloro-5-(6-(dimethylamino)-2-methoxypyridin-3-yl)-1H-indole-3-carboxylic acid
SMILES
O=C(C1=CNC2=C1C=C(C3=CC=C(N(C)C)N=C3OC)C(Cl)=C2)O
Molecular Formula
C17H16ClN3O3
CAS Number
1467059-70-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for PF-06885249 biochemical
PF-06885249 (PF06885249) is a potent, direct AMPK activator with EC50 of 7.0 and 27nM for alpha1beta1gamma1 and alpha2beta1gamma1, respectively; displays no activity for alpha1beta2gamma1, alpha2beta2gamma1 and alpha2beta2gamma3 complexes (EC50>40uM).
Product Categories/Family for PF-06885249 biochemical
References
1. Ryder T, et al. J Med Chem. 2018 Jul 23. doi: 10.1021/acs.jmedchem.8b00807.
Similar Products
Product Notes
The PF-06885249 (Catalog #AAA3602001) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PF-06885249, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
