Structure
Perifosine Biochemical
Perifosine
Purity
>98% (HPLC)
Synonyms
Perifosine; KRX-0401; NSC 639966; D-21266; KRX 0401; KRX0401; D21266; D 21266; Perifosine biochemical
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
Akt
Receptor
Akt
Chemical Name
Piperidinium, 4-[[hydroxy(octadecyloxy)phosphinyl]oxy]-1, 1-dimethyl-, inner salt
SMILES
O=P(OC1CC[N+](C)(C)CC1)([O-])OCCCCCCCCCCCCCCCCCC
Molecular Formula
C25H52NO4P
CAS Number
157716-52-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Perifosine biochemical
A oral bioavailable alkylphospholipid that displays significant antiproliferative activity in vitro and in vivo in several human tumor model; acts as an Akt inhibitor and a PI3K inhibitor, induces p21 (WAF1) expression in squamous carcinoma cells through a p53-independent pathway; enhances apoptosis and inhibits the growth of xenografts in nude mice combined with a lysosomal inhibitor. Brain Cancer Phase 2 Clinical
Product Categories/Family for Perifosine biochemical
References
1. Kondapaka SB, et al. Mol Cancer Ther. 2003 Nov; 2 (11):1093-103.
2. Patel V, et al. Cancer Res. 2002 Mar 1; 62 (5):1401-9.
3. Becher OJ, et al. Cancer Res. 2010 Mar 15; 70 (6):2548-57.
2. Patel V, et al. Cancer Res. 2002 Mar 1; 62 (5):1401-9.
3. Becher OJ, et al. Cancer Res. 2010 Mar 15; 70 (6):2548-57.
Similar Products
Product Notes
The Perifosine (Catalog #AAA3602254) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Perifosine, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
