Structure
(Structure of 045126.)
Pam3Cys-Ser-(Lys)4•3HCl Biochemical
Pam3Cys-Ser-(Lys)4•3HCl (Pam3CSK4, Pam3Cys-SKKKK, (S)-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH)
Purity
Highly PurifiedAbsence of detectable protein or DNA contaminants with agonistic TLR activity.
Synonyms
Pam3Cys-Ser-(Lys)4•3HCl; Pam3Cys-Ser-(Lys)4•3HCl (Pam3CSK4; Pam3Cys-SKKKK; (S)-[2; 3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH); Pam3Cys-Ser-(Lys)4•3HCl biochemical
Purity/Purification
Highly Purified
Absence of detectable protein or DNA contaminants with agonistic TLR activity.
Absence of detectable protein or DNA contaminants with agonistic TLR activity.
CAS Number
112208-00-1
Molecular Formula
C81H156N10O13S. 3HCl
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Stable for at least 2 years after receipt when stored at -20 degree C.
Long-term Storage: -20 degree C
Stable for at least 2 years after receipt when stored at -20 degree C.
Structure
(Structure of 045126.)
Structure
(Structure of 045126.)
Related Product Information for Pam3Cys-Ser-(Lys)4•3HCl biochemical
Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response, enhances IgG2a and IgG1 titers and upregulates proinflammatory and Th1 cytokine genes. Potent activator of the proinflammatory transcription factor NF-kappaB. Activates/represses at least 140 genes involved in signal transduction and regulation of the immune response.
Product Categories/Family for Pam3Cys-Ser-(Lys)4•3HCl biochemical
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Product Notes
The Pam3Cys-Ser-(Lys)4•3HCl (Catalog #AAA6092307) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Pam3Cys-Ser-(Lys)4•3HCl, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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