Structure
Oritavancin diphosphate Biochemical
Oritavancin diphosphate
Purity
>=98% by HPLC
Synonyms
Oritavancin diphosphate; (4"R)-22-O-(3-amino-2; 3; 6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-N3"-[(4'-chloro[1; 1'-biphenyl]-4-yl)methyl]-vancomycin; diphosphate; LY 333328; LY-333328; Oritavancin diphosphate biochemical
Specificity
A semi-synthetic glycopeptide antibiotic
Purity/Purification
>=98% by HPLC
Form/Format
White to off-white solid
Solubilities
~10mg/ml Water
Molecular Formula
C??H??Cl?N??O??-2H?PO?
InChi
InChI=1S/C86H97Cl3N10O26.2H3O4P/c1-35(2)22-51(92-7)77(110)98-67-69(105)42-15-20-55(49(88)24-42)120-57-26-44-27-58(73(57)125-84-74(71(107)70(106)59(34-100)122-84)124-62-32-86(6; 76(109)37(4)119-62)93-33-38-8-10-39(11-9-38)40-12-17-45(87)18-13-40)121-56-21-16-43(25-50(56)89)72(123-61-31-85(5; 91)75(108)36(3)118-61)68-82(115)97-66(83(116)117)48-28-46(101)29-54(103)63(48)47-23-41(14-19-53(47)102)64(79(112)99-68)96-80(113)65(44)95-78(111)52(30-60(90)104)94-81(67)114;2*1-5(2; 3)4/h8-21; 23-29; 35-37; 51-52;InChi Key
SMILES
OP(O)(O)=O.OP(O)(O)=O.O[C@@H]1[C@@H](O[C@@](O[C@@H](C)[C@@H]2O)([H])C[C@]2(C)NCC3=CC=C(C4=CC=C(Cl)C=C4)C=C3)[C@@H](O[C@H](CO)[C@H]1O)OC5=C(OC6=CC=C([C@H]([C@H]7NC([C@H](NC)CC(C)C)=O)O)C=C6Cl)C=C([C@](NC([C@@H](NC7=O)CC(N)=O)=O)([H])C(N[C@](C8=O)([H])C9=CC%10=C(O)C=C9)=O)C=C5OC%11=CC=C([C@H]([C@](C(N[C@@](C(O)=O)([H])C%12=C%10C(O)=CC(O)=C%12)=O)([H])N8)O[C@]%13([H])O[C@@H](C)[C@H](O)[C@@](C)(N)C%13)C=C%11Cl
CAS Number
192564-14-0
MDL Number
MFCD29472248
PubChem CID
53297457
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Structure
Structure
Related Product Information for Oritavancin diphosphate biochemical
Oritavancin diphosphate is a second-generation, semi-synthetic lipoglycopeptide, that is derived from chloroeremomycin, an analogue of vancomycin. Similar to vancomycin, it contains a core heptapeptide; however, its unique lipophilic side chain provides oritavancin with a prolonged half-life compared to the parent drug. Oritavancin has a multifaceted mechanism of action that displays concentration-dependent effects against gram-positive organisms. Similar to vancomcyin and other glycopeptides, oritavancin inhibits cell wall biosynthesis by binding noncovalently to the D-alanyl-D-alanine terminal ends of the peptidoglycan chain and pentaglycine bridge, thereby inhibiting transglycosylation and transpeptidation.
Product Categories/Family for Oritavancin diphosphate biochemical
References
ubchem.ncbi.nlm.nih.gov/compound/53297457
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Product Notes
The Oritavancin diphosphate (Catalog #AAA8400353) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Oritavancin diphosphate, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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