Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Structure

NKL 22 biochemical

NKL 22 (MDK-4154)

Purity
>=98% by HPLC
Synonyms
NKL 22; NKL 22 (MDK-4154); N1- (2-aminophenyl)-N7-phenylheptanediamide; NKL 22 biochemical
Ordering
For Research Use Only!
Purity/Purification
>=98% by HPLC
Form/Format
Beige to pale white solid
Salt Form
No
CAS Number
537034-15-4
Cell-Permeable
Yes
Reconstitution
DMSO (100 mg/ml)
SMILES
C1=CC=C(C=C1)NC(=O)CCCCCC(=O)NC2=CC=CC=C2N
InChi
1S/C19H23N3O2/c20-16-11-7-8-12-17(16)22-19(24)14-6-2-5-13-18(23)21-15-9-3-1-4-10-15/h1,3-4,7-12H,2,5-6,13-14,20H2,(H,21,23)(H,22,24)
InChi Key
ZAIULUYKQLVQFH-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.

Structure

Structure
Related Product Information for NKL 22 biochemical
NKL 22 (also known as MDK-4154) is a cell-permeable compound that acts as a FXN- (frataxin gene) specific HDAC (histone deacetylase) inhibitor. It reverses the silencing of FXN transcription in FRDA (Friedreich's ataxia) cells due to hypoacetylation of histones H3 and H4 by increasing acetylation at H3K14; H4K12; and H4K5 without much acetylation on H3K9; H4K8 and H4K16.

Similar Products

Product Notes

The NKL 22 (Catalog #AAA846276) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NKL 22, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.