Structure
Lenvatinib Biochemical
Lenvatinib
Purity
>=98% by HPLC
Synonyms
Lenvatinib; 4-[3-chloro-4- (cyclopropylcarbamoylamino) phenoxy]-7-methoxyquinoline-6-carboxamide; E7080; Lenvatinib biochemical
Purity/Purification
>=98% by HPLC
Form/Format
Crystalline solid
Salt Form
No
CAS Number
417716-92-8
Cell-Permeable
Yes
Reconstitution
DMSO (>35 mg/ml)
SMILES
COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
InChi
InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)
InChi Key
WOSKHXYHFSIKNG-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Protect from air and light.
Structure
Structure
Related Product Information for Lenvatinib biochemical
Lenvatinib is a potent inhibitor of multiple receptor tyrosine kinases; with IC50 values of 22 nM; 4 nM; 5.2 nM; 39 nM and 35 nM on VEGFR-1; VEGFR-2; VEGFR-3; PDGFRbeta and RET; respectively. It inhibits SCF- and VEGF-induced angiogenesis of human umbilical vein endothelial cells that express the SCF receptor KIT; with IC50 values of 5.2 nM and 5.1 nM; respectively. Lenvatinib inhibits tumor growth in the human small cell lung cancer H146 xenograft model.
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Product Notes
The Lenvatinib (Catalog #AAA846300) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Lenvatinib, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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