Structure
GW-3965 hydrochloride Biochemical
GW-3965 hydrochloride
Purity
>=98% by HPLC
Synonyms
GW-3965 hydrochloride; 2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2; 2-diphenylethyl)amino)propoxy)phenyl)acetic Acid hydrochloride; GW-3965 hydrochloride biochemical
Purity/Purification
>=98% by HPLC
Form/Format
Appearance: White solid
CAS Number
405911-17-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
16078973
Solubility/Reconstitution Instructions
DMSO (>50 mg/ml)
SMILES
C1=CC=C(C=C1)C(CN(CCCOC2=CC=CC(=C2)CC(=O)O)CC3=C(C(=CC=C3)C(F)(F)F)Cl)C4=CC=CC=C4.Cl
InChi
InChI=1S/C33H31ClF3NO3.ClH/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26;/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40);1H
InChi Key
NMPUWJFHNOUNQU-UHFFFAOYSA-N
Handling
Protect from air and moisture
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Shelf Life: 36 months
Structure
Structure
Related Product Information for GW-3965 hydrochloride biochemical
Background: GW-3965 hydrochloride is a non-steroidal liver X receptor agonist on hLXRalpha and hLXRbeta. GW3965 has an EC?? = 125 nM in a cell-free ligand-sensing assay of LXRalpha and profiles as a full agonist on hLXRalpha and hLXRbeta in cell-based assays with EC?? = 190 nM and 30 nM, respectively. Up-regulates ABCA1 gene expression and raises circulating HDL levels. Displays potent antiatherogenic activity in mouse models of atherosclerosis.
Product Categories/Family for GW-3965 hydrochloride biochemical
Similar Products
Product Notes
The GW-3965 hydrochloride (Catalog #AAA843178) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "GW-3965 hydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
