Structure
Efonidipine hydrochloride Biochemical
Efonidipine hydrochloride
Purity
>98% (HPLC)
Synonyms
Efonidipine hydrochloride; NZ-105 hydrochloride; Efonidipine hydrochloride biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 8.5mg/mL
Target
Calcium Channel
Receptor
Calcium Channel
Chemical Name
3-Pyridinecarboxylic acid, 5-(5, 5-dimethyl-2-oxido-1, 3, 2-dioxaphosphorinan-2-yl)-1, 4-dihydro-2, 6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester, hydrochloride(1:1)
SMILES
CC1=C(C(C(=C(N1)C)P2(=O)OCC(CO2)(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5.Cl
Molecular Formula
C34H39ClN3O7P
CAS Number
111011-53-1
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Efonidipine hydrochloride biochemical
Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker, exhibits antihypertensive effect through vasodilatation; increases coronary blood flow by blocking L & T-type calcium channels and attenuates myocardial ischaemia, lowers blood pressure in cerebral resistance vessels and prevents hypertension induced brain damage; increases glomerular filtration rate without increasing intra-glomerular pressure and filtration fraction.
Product Categories/Family for Efonidipine hydrochloride biochemical
References
1. Masuda Y, et al. Arch Int Pharmacodyn Ther. 1990 Mar-Apr; 304:247-64.
2. Tamura T, et al. Naunyn Schmiedebergs Arch Pharmacol. 1991 Apr; 343 (4):405-10.
3. Shudo C, et al. Gen Pharmacol. 1994 Nov; 25 (7):1451-8.
4. Yamashita T, et al. Jpn J Pharmacol. 1991 Nov; 57 (3):337-48.
2. Tamura T, et al. Naunyn Schmiedebergs Arch Pharmacol. 1991 Apr; 343 (4):405-10.
3. Shudo C, et al. Gen Pharmacol. 1994 Nov; 25 (7):1451-8.
4. Yamashita T, et al. Jpn J Pharmacol. 1991 Nov; 57 (3):337-48.
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Product Notes
The Efonidipine hydrochloride (Catalog #AAA3600408) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Efonidipine hydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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