Structure
DprE1-IN-1 Biochemical
DprE1-IN-1
Purity
>98% (HPLC)
Synonyms
DprE1-IN-1; TBA-7371; TBA 7371; TBA7371; DprE1-IN-1 biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 11mg/mL (30.95mM)
Target
CDK
Receptor
DprE1
Chemical Name
N-(2-hydroxyethyl)-1-((6-methoxy-5-methylpyrimidin-4-yl)methyl)-6-methyl-1H-pyrrolo[3, 2-b]pyridine-3-carboxamide
SMILES
Cc1cc2c(c(cn2Cc2c(c(ncn2)OC)C)C(=O)NCCO)nc1
Molecular Formula
C18H21N5O3
CAS Number
1494675-86-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for DprE1-IN-1 biochemical
TBA-7371 is a non-covalent inhibitor of decaprenylphosphoryl-beta-D-ribose 2'-epimerase (DprE1) with an IC50 value of 10nM. It also inhibits PDE6 with an IC50 value of 4uM.1 AZ 7371 has been shown to be active against M. tuberculosis with an MIC range of 0.78-3.12uM and demonstrates efficacy in a rodent model of tuberculosis.
Product Categories/Family for DprE1-IN-1 biochemical
References
1. Shirude PS, et al. J Med Chem. 2014 Jul 10; 57 (13):5728-37.
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Product Notes
The DprE1-IN-1 (Catalog #AAA3607317) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "DprE1-IN-1, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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