Structure
CP-31398 dihydrochloride Biochemical
CP-31398 dihydrochloride
Purity
>98% (HPLC)
Synonyms
CP-31398 dihydrochloride; CP31398 dihydrochloride; CP-31398 dihydrochloride biochemical
Purity/Purification
>98% (HPLC)
Target
MDM2-p53
Receptor
MDM2-p53
Chemical Name
N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N, N-dimethyl-1, 3-propanediamine dihydrochloride
SMILES
CN(C)CCCNC1=C2C=CC=CC2=NC(/C=C/C3=CC=C(OC)C=C3)=N1.[H]Cl.[H]Cl
Molecular Formula
C22H26N4O.2HCl
CAS Number
1217195-61-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CP-31398 dihydrochloride biochemical
CP-31398 is a small molecule p53 reactivator that protects p53 from thermal denaturation, not only reactivates mutant p53 but also induces stabilization of wild type p53; shows anti-tumor activity in vivo in a transgenic UPII-SV40T mouse model of bladder transitional cell carcinoma.
References
1. Foster BA, et al. Science. 1999 Dec 24; 286 (5449):2507-10.
2. Madka V, et al. Neoplasia. 2013 Aug; 15 (8):966-74.
3. Wang W, et al. Mol Cell Biol. 2003 Mar; 23 (6):2171-81.
2. Madka V, et al. Neoplasia. 2013 Aug; 15 (8):966-74.
3. Wang W, et al. Mol Cell Biol. 2003 Mar; 23 (6):2171-81.
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Product Notes
The CP-31398 dihydrochloride (Catalog #AAA3600814) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CP-31398 dihydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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