Coumarin-SAHA Biochemical

Coumarin-SAHA

Cat. Num. AAA848940

• Purity: >=98%
• Synonyms: Coumarin-SAHA; Coumarin-suberoylanilide hydroxamic acid; N1-Hydroxy-N8- (4-methyl-2-oxo-2H-chromen-7-yl) octanediamide; Coumarin-SAHA biochemical

• Purity/Purification: >=98%
• Form/Format: Crystalline solid

• Solubility: ~5 mg/ml in DMSO and DMF
• Molecular Formula: C??H??N?O?
• CAS Number: 1260635-77-5
• PubChem CID: 53393956
• SMILES: CC1=CC (=O)OC2=C1C=CC (=C2)NC (=O)CCCCCCC (=O)NO
• InChi: InChI=1S/C18H22N2O5/c1-12-10-18 (23)25-15-11-13 (8-9-14 (12)15)19-16 (21)6-4-2-3-5-7-17 (22)20-24/h8-11,24H,2-7H2,1H3, (H,19,21)(H,20,22)
• InChi Key: YSRCADVJNRJJAV-UHFFFAOYSA-N
• Preparation and Storage: Store at -20 degree C; Shelf life: ~36 months

Structure

Related Product Information for Coumarin-SAHA biochemical

Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor. It is a fluorescent probe that competitively binds HDAC. It is a SAHA derivative where the anilino "cap" group is replaced by 7-amino-4-methylcoumarin. The fluorescence excitation and emission maxima of free c-SAHA is 325 and 400 nm, respectively. Fluorescence is quenched by 50% when bound to HDAC8.

Product Categories/Family for Coumarin-SAHA biochemical

Cancer Research; Epigenetic Regulation; Eraser Enzymes; Histone Deacetylases (HDACs); HDAC Inhibitors; Biochemicals; Enzyme Inhibitors; Histone Deacetylase (HDAC) Inhibitors; Biochemicals (A-Z); Cancer Research; Cell Damage & Oxidative Stress; Inhibitors;

References

https://pubchem.ncbi.nlm.nih.gov/compound/53393956