Structure
Chidamide Biochemical
Chidamide
Purity
>=98%
Synonyms
Chidamide; N-?(2-?amino-?5-?fluorophenyl)-?4-?[[[1-?oxo-?3-?(3-?pyridinyl)-?2-?propen-?1-?yl]amino]methyl]-?benzamide; Chidamide biochemical
Purity/Purification
>=98%
Form/Format
Appearance: White to off-white solid
CAS Number
743420-02-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
53394037
Solubility/Reconstitution Instructions
DMSO
SMILES
C1=CC(=CN=C1)C=CC(=O)NCC2=CC=C(C=C2)C(=O)NC3=C(C=CC(=C3)F)N
InChi
InChI=1S/C22H19FN4O2/c23-18-8-9-19(24)20(12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13H,14,24H2,(H,26,28)(H,27,29)
InChi Key
WXHHICFWKXDFOW-UHFFFAOYSA-N
Handling
Protect from light and mositure
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Shelf Life: 24 months
Structure
Structure
Related Product Information for Chidamide biochemical
Background: Cell-permeable. A new benzamide class of histone deacetylase (HDAC) inhibitor with marked anti-tumor activity. It increases histone H3 acetylation levels in LoVo and HT29 colon cancer cells at concentrations as low as 4 uM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells.
Product Categories/Family for Chidamide biochemical
Similar Products
Product Notes
The Chidamide (Catalog #AAA842324) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Chidamide, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
