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Structure

Aurora Kinase B Inhibitor (AZD1152-HQPA) Biochemical

Aurora Kinase B Inhibitor (AZD1152-HQPA)

Purity
>=99% by HPLC
Synonyms
Aurora Kinase B Inhibitor (AZD1152-HQPA); AZD1152-HQPA; Aurora Kinase B Inhibitor (AZD1152-HQPA) biochemical
Ordering
For Research Use Only!
Purity/Purification
>=99% by HPLC
Form/Format
Appearance: Crystalline solid
CAS Number
722544-51-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD10687152
PubChem CID
16007391
Solubility/Reconstitution Instructions
DMSO
SMILES
CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO
InChi
InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)
InChi Key
QYZOGCMHVIGURT-UHFFFAOYSA-N
Handling
Protect from light and moisture
Preparation and Storage
At -20 degree C
Shelf Life: 24 months

Structure

Structure
Related Product Information for Aurora Kinase B Inhibitor (AZD1152-HQPA) biochemical
Background: A potent and specific Aurora kinase B inhibitor. It is 1000-fold more selective for aurora kinase B than for aurora kinase A (Ki values of 1300 nM and 0.36 nM for aurora kinase A and B, respectively). At concentrations as low as 0.01 uM, AZD 1152 produced a significant (p<0.05) decrease in the ability of NB4 cells to proliferate by 48 hours.

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Product Notes

The Aurora Kinase B Inhibitor (AZD1152-HQPA) (Catalog #AAA842617) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Aurora Kinase B Inhibitor (AZD1152-HQPA), Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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