Mouse anti-Human SLC29A2 Polyclonal Antibody | anti-SLC29A2 antibody
SLC29A2 (Equilibrative Nucleoside Transporter 2, 36 kDa Nucleolar Protein HNP36, Delayed-early Response Protein 12, Equilibrative Nitrobenzylmercaptopurine Riboside-insensitive Nucleoside Transporter, Equilibrative NBMPR-insensitive Nucleoside Transporter
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: Immunofluorescence: 10ug/ml
Western Blot (WB)
(Western Blot analysis of SLC29A2 expression in transfected 293T cell line by SLC29A2 polyclonal antibody. Lane 1: SLC29A2 transfected lysate (50.16kD). Lane 2: Non-transfected lysate.)
Immunofluorescence (IF)
(Immunofluorescence of purified antibody to SLC29A2 on HeLa cell. [antibody concentration 10ug/ml])
NCBI and Uniprot Product Information
NCBI Description
The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008]
Uniprot Description
SLC29A2: Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine. Belongs to the SLC29A/ENT transporter (TC 2.A.57) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: nuclear membrane; integral to plasma membrane; basolateral plasma membrane; nucleolus; plasma membrane
Molecular Function: nucleoside transmembrane transporter activity
Biological Process: cell proliferation; nucleoside transport; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; transmembrane transport
Research Articles on SLC29A2
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Product Notes
The SLC29A2 slc29a2 (Catalog #AAA6008474) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SLC29A2 (Equilibrative Nucleoside Transporter 2, 36 kDa Nucleolar Protein HNP36, Delayed-early Response Protein 12, Equilibrative Nitrobenzylmercaptopurine Riboside-insensitive Nucleoside Transporter, Equilibrative NBMPR-insensitive Nucleoside Transporter reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC29A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Suitable for use in Immunofluorescence and Western Blot. Dilution: Immunofluorescence: 10ug/ml. Researchers should empirically determine the suitability of the SLC29A2 slc29a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MARGDAPRDS YHLVGISFFI LGLGTLLPWN FFITAIPYFQ ARLAGAGNST ARILSTNHTG PEDAFNFNNW VTLLSQLPLL LFTLLNSFLY QCVPETVRIL GSLLAILLLF ALTAALVKVD MSPGPFFSIT MASVCFINSF SAVLQGSLFG QLGTMPSTYS TLFLSGQGLA GIFAALAMLL SMASGVDAET SALGYFITPC VGILMSIVCY LSLPHLKFAR YYLANKSSQA QAQELETKAE LLQSDENGIP SSPQKVALTL DLDLEKEPES EPDEPQKPGK PSVFTVFQKI WLTALCLVLV FTVTLSVFPA ITAMVTSSTS PGKWSQFFNP ICCFLLFNIM DWLGRSLTSY FLWPDEDSRL LPLLVCLRFL FVPLFMLCHV PQRSRLPILF PQDAYFITFM LLFAVSNGYL VSLTMCLAPR QVLPHEREVA GALMTFFLAL GLSCGASLSF LFKALL. It is sometimes possible for the material contained within the vial of "SLC29A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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