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Structure (Structure of A0001-68U)

A-769662 Biochemical

A-769662 (6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile)

Purity
Highly Purified
~99%
Synonyms
A-769662; A-769662 (6; 7-Dihydro-4-hydroxy-3-(2'-hydroxy[1; 1'-biphenyl]-4-yl)-6-oxo-thieno[2; 3-b]pyridine-5-carbonitrile); A-769662 biochemical
Ordering
For Research Use Only!
Purity/Purification
Highly Purified
~99%
Form/Format
Supplied as an off-white powder.
CAS Number
844499-71-4
Molecular Formula
C20H12N2O3S
Elemental Analysis
Calculated
C: 64.25%
H: 3.64%
N: 7.49%
S: 8.58%
Melting Point
277-280ºC
Solubility
Soluble in DMSO at 33mg/ml; soluble in ethanol at 5mg/ml with slight warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 50-100uM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
Preparation and Storage
May be stored at RT for short-term only. Long-term storage is recommended at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Structure

(Structure of A0001-68U)

Structure (Structure of A0001-68U)
Related Product Information for A-769662 biochemical
A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an alpha beta gamma heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the B1 subunit. A-769662 activates AMPK through the beta subunit carbohydrate-binding module and the gamma subunit but not the AMP-binding sites.
Product Categories/Family for A-769662 biochemical

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Product Notes

The A-769662 (Catalog #AAA6042305) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "A-769662, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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