Human basic helix-loop-helix family, member e41 ELISA Kit | BHLHE41 elisa kit
Human Class E basic helix-loop-helix protein 41, BHLHE41 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, Feb 2014]
Uniprot Description
BHLHB3: May be a transcriptional repressor that represses both basal and activated transcription. Homodimerize.
Chromosomal Location of Human Ortholog: 12p12.1
Cellular Component: nucleus
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; MRF binding; protein homodimerization activity; protein heterodimerization activity; histone deacetylase binding; bHLH transcription factor binding; transcription corepressor activity
Biological Process: circadian rhythm; transcription from RNA polymerase II promoter; cell proliferation; organ morphogenesis; negative regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; cell differentiation; negative regulation of transcription, DNA-dependent
Disease: Short Sleeper
Research Articles on BHLHE41
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Product Notes
The Human BHLHE41 bhlhe41 (Catalog #AAA9332323) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9332323 ELISA Kit recognizes Human BHLHE41. It is sometimes possible for the material contained within the vial of "basic helix-loop-helix family, member e41, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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