Alkaline nuclease BGLF5 (BGLF5) Recombinant Protein | BGLF5 recombinant protein
Recombinant Epstein-Barr virus Alkaline nuclease BGLF5 (BGLF5)
NCBI and Uniprot Product Information
Uniprot Description
Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules. Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate. Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides. Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity. Also acts as a cytoplasmic RNA endonuclease that induces degradation of the majority of the cellular messenger RNAs during early lytic infection. The resulting inhibition of cellular protein synthesis serves to ensure maximal viral gene expression and evasion from host immune response. Internally cleaves host mRNAs which are then degraded by the cellular exonuclease XRN1. Bypasses therefore the regulatory steps of deadenylation and decapping normally required for XRN1 activation.
Research Articles on BGLF5
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Product Notes
The BGLF5 bglf5 (Catalog #AAA1106475) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-470, Full length protein. The amino acid sequence is listed below: MADVDELEDP MEEMTSYTFA RFLRSPETEA FVRNLDRPPQ MPAMRFVYLY CLCKQIQEFS GETGFCDFVS SLVQENDSKD GPSLKSIYWG LQEATDEQRT VLCSYVESMT RGQSENLMWD ILRNGIISSS KLLSTIKNGP TKVFEPAPIS TNHYFGGPVA FGLRCEDTVK DIVCKLICGD ASANRQFGFM ISPTDGIFGV SLDLCVNVES QGDFILFTDR SCIYEIKCRF KYLFSKSEFD PIYPSYTALY KRPCKRSFIR FINSIARPTV EYVPDGRLPS EGDYLLTQDE AWNLKDVRKR KLGPGHDLVA DSLAANRGVE SMLYVMTDPS ENAGRIGIKD RVPVNIFINP RHNYFYQVLL QYKIVGDYVR HSGGGKPGRD CSPRVNIVTA FFRKRSPLDP ATCTLGSDLL LDASVEIPVA VLVTPVVLPD SVIRKTLSTA AGSWKAYADN TFDTAPWVPS GLFADDESTP. It is sometimes possible for the material contained within the vial of "Alkaline nuclease BGLF5 (BGLF5), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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