Beclin 2 Blocking Peptide | BECN1P1 blocking peptide
Beclin 2 Peptide
Gene Names
BECN2; BECN1L1; BECN1P1
Applications
Blocking (BL)
Synonyms
Beclin 2; Beclin 2 Peptide; BECN2; BECN1L1; Beclin-1-like protein 1; Beclin 1 autophagy related pseudogene 1; BECN1P1; beclin 1; autophagy related; pseudogene 1; BECN1P1 blocking peptide
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Positions
16 amino acid peptide near the amino terminus of human Beclin 2.
Sequence
PGVTTREVTDAEEQQD
Sequence Length
431
Applicable Applications for BECN1P1 blocking peptide
Blocking (BL)
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Species
Human
Preparation and Storage
Store at -20 degree C, stable for one year.
References
1. Gozuacik D and Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene. 2004; 23:2891-906. 2. Kisen GO, Tessitore L, Costelli P, et al. Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells. Carcinogenesis 1993; 14:2501-5. 3. He C, Wei Y, Sun K, et al. Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism. Cell 2013; 154:1085-99. 4. Zhang W and He C. Regulation of plasma membrane receptors by a new autophagy-related BECN/Beclin family member. Autophagy 2014; 10: epub.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48,153 Da
NCBI Official Full Name
beclin-2
NCBI Official Synonym Full Names
beclin 2
NCBI Official Symbol
BECN2
NCBI Official Synonym Symbols
BECN1L1; BECN1P1
NCBI Protein Information
beclin-2
UniProt Protein Name
Beclin-2
UniProt Gene Name
BECN2
Uniprot Description
BECN1L1: May play a role in autophagy and antiviral host defense (Potential). Belongs to the beclin family.
Chromosomal Location of Human Ortholog: 1q43
Cellular Component: cytoplasmic vesicle
Molecular Function: protein binding
Biological Process: autophagic vacuole formation; autophagy; cellular response to nitrogen starvation; CVT pathway; endosome to lysosome transport; late endosome to vacuole transport
Research Articles on BECN1P1
Similar Products
Product Notes
The BECN1P1 becn2 (Catalog #AAA154485) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 16 amino acid peptide near the amino terminus of human Beclin 2. AAA Biotech's Beclin 2 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Researchers should empirically determine the suitability of the BECN1P1 becn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PGVTTREVTD AEEQQD. It is sometimes possible for the material contained within the vial of "Beclin 2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
